Caligan Partners LP: TYRA BIOSCIENCES INC (TYRA): Quarterly 13F Position History
As of Q1 2026, Caligan Partners LP reported 1,276,968 shares of TYRA BIOSCIENCES INC (TYRA), worth $48.9M and representing 3.5% of its 13F equity book. Quarter-over-quarter share count change: + 332,711 (+35.2%) . The position first appeared in Q1 2025 and has been disclosed across 5 13F-HR filings in Pactolio's tracked window.
- 1,276,968Shares Held (Latest Filing)
- $48.9MReported Market Value (Latest Filing)
- 3.5%Portfolio Weight (% of 13F Equity Book)
- +332,711Quarter-over-Quarter Share Change
- +$24.1MQuarter-over-Quarter Value Change
- 1,276,968Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 5 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 1,276,968 | +332,711 | +35.2% | $48.9M | 3.5% | $38.3 |
| Q4 2025 | 944,257 | +247,432 | +35.5% | $24.8M | 2.3% | $26.3 |
| Q3 2025 | 696,825 | +506,875 | +266.8% | $9.7M | 1.4% | $14.0 |
| Q2 2025 | 189,950 | +164,950 | +659.8% | $1.8M | 0.4% | $9.6 |
| Q1 2025 | 25,000 | — | — | $232.5K | 0.0% | $9.3 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did Caligan Partners LP first disclose a TYRA position in 13F-HR filings?
Caligan Partners LP first reported TYRA BIOSCIENCES INC (TYRA) on its 13F-HR filing for the period ending 2025-03-31 (Q1 2025). The position has appeared on 5 reported quarters within Pactolio's tracked window.
What was Caligan Partners LP's most recent quarter-over-quarter share-count change in TYRA?
Between Q4 2025 and Q1 2026, Caligan Partners LP added 332,711 shares of TYRA (+35.2%), bringing the total reported position to 1,276,968 shares at a market value of $48.9M.
Does the implied price-per-share represent Caligan Partners LP's cost basis in TYRA?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.