Commodore Capital LP — TYRA BIOSCIENCES INC TYRA: Quarterly 13F Position History
Commodore Capital LP has reported TYRA BIOSCIENCES INC (TYRA) on 5 13F-HR filings in Pactolio's tracked window, first appearing in Q1 2025. As of Q1 2026, the position is sized at 2,475,000 shares ($94.8M market value, 5.48% of the equity book). Quarter-over-quarter share count change: 900,000 (-26.7%) .
- 2,475,000Shares Held (Latest Filing)
- $94.8MReported Market Value (Latest Filing)
- 5.48%Portfolio Weight (% of 13F Equity Book)
- 900,000Quarter-over-Quarter Share Change
- +$6.1MQuarter-over-Quarter Value Change
- 3,375,000Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 5 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 2,475,000 | 900,000 | -26.7% | $94.8M | 5.48% | $38.30 |
| Q4 2025 | 3,375,000 | 0 | — | $88.7M | 5.91% | $26.29 |
| Q3 2025 | 3,375,000 | +275,000 | +8.9% | $47.2M | 2.31% | $13.99 |
| Q2 2025 | 3,100,000 | +2,150,000 | +226.3% | $29.7M | 2.09% | $9.57 |
| Q1 2025 | 950,000 | — | — | $8.8M | 0.65% | $9.30 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did Commodore Capital LP first disclose a TYRA position in 13F-HR filings?
Commodore Capital LP first reported TYRA BIOSCIENCES INC (TYRA) on its 13F-HR filing for the period ending 2025-03-31 (Q1 2025). The position has appeared on 5 reported quarters within Pactolio's tracked window.
What was Commodore Capital LP's most recent quarter-over-quarter share-count change in TYRA?
Between Q4 2025 and Q1 2026, Commodore Capital LP reduced its TYRA position by 900,000 shares (-26.7%), leaving 2,475,000 shares at a market value of $94.8M.
Does the implied price-per-share represent Commodore Capital LP's cost basis in TYRA?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.