RTW INVESTMENTS, LP: MADRIGAL PHARMACEUTICALS INC (MDGL): Quarterly 13F Position History
As of Q1 2026, RTW INVESTMENTS, LP reported 1,993,687 shares of MADRIGAL PHARMACEUTICALS INC (MDGL), worth $1.0B and representing 10.4% of its 13F equity book. The position first appeared in Q2 2023 and has been disclosed across 12 13F-HR filings in Pactolio's tracked window.
- 1,993,687Shares Held (Latest Filing)
- $1.0BReported Market Value (Latest Filing)
- 10.4%Portfolio Weight (% of 13F Equity Book)
- 0Quarter-over-Quarter Share Change
- -$117.4MQuarter-over-Quarter Value Change
- 1,993,687Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 12 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 1,993,687 | 0 | — | $1.0B | 10.4% | $523.5 |
| Q4 2025 | 1,993,687 | 0 | — | $1.2B | 11.6% | $582.3 |
| Q3 2025 | 1,993,687 | 0 | — | $914.4M | 11.3% | $458.7 |
| Q2 2025 | 1,993,687 | 0 | — | $603.4M | 8.6% | $302.6 |
| Q1 2025 | 1,993,687 | 0 | — | $660.4M | 10.1% | $331.2 |
| Q4 2024 | 1,993,687 | 0 | — | $615.2M | 9.3% | $308.6 |
| Q3 2024 | 1,993,687 | +77,825 | +4.1% | $423.1M | 6.1% | $212.2 |
| Q2 2024 | 1,915,862 | +1,518,815 | +382.5% | $536.7M | 8.3% | $280.2 |
| Q1 2024 | 397,047 | 418,144 | -51.3% | $106.0M | 1.6% | $267.0 |
| Q4 2023 | 815,191 | +505,706 | +163.4% | $188.6M | 2.9% | $231.4 |
| Q3 2023 | 309,485 | +87,923 | +39.7% | $45.2M | 1.0% | $146.0 |
| Q2 2023 | 221,562 | — | — | $51.2M | 1.0% | $231.0 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did RTW INVESTMENTS, LP first disclose a MDGL position in 13F-HR filings?
RTW INVESTMENTS, LP first reported MADRIGAL PHARMACEUTICALS INC (MDGL) on its 13F-HR filing for the period ending 2023-06-30 (Q2 2023). The position has appeared on 12 reported quarters within Pactolio's tracked window.
What was RTW INVESTMENTS, LP's most recent quarter-over-quarter share-count change in MDGL?
RTW INVESTMENTS, LP held the same 1,993,687 shares of MDGL between Q4 2025 and Q1 2026 — the reported share count was unchanged quarter-over-quarter.
Does the implied price-per-share represent RTW INVESTMENTS, LP's cost basis in MDGL?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.