RTW INVESTMENTS, LP — MADRIGAL PHARMACEUTICALS INC MDGL: Quarterly 13F Position History
RTW INVESTMENTS, LP has reported MADRIGAL PHARMACEUTICALS INC (MDGL) on 12 13F-HR filings in Pactolio's tracked window, first appearing in Q2 2023. As of Q1 2026, the position is sized at 1,993,687 shares ($1.04B market value, 10.38% of the equity book).
- 1,993,687Shares Held (Latest Filing)
- $1.04BReported Market Value (Latest Filing)
- 10.38%Portfolio Weight (% of 13F Equity Book)
- 0Quarter-over-Quarter Share Change
- -$117.4MQuarter-over-Quarter Value Change
- 1,993,687Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 12 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 1,993,687 | 0 | — | $1.04B | 10.38% | $523.47 |
| Q4 2025 | 1,993,687 | 0 | — | $1.16B | 11.63% | $582.34 |
| Q3 2025 | 1,993,687 | 0 | — | $914.4M | 11.27% | $458.66 |
| Q2 2025 | 1,993,687 | 0 | — | $603.4M | 8.59% | $302.64 |
| Q1 2025 | 1,993,687 | 0 | — | $660.4M | 10.10% | $331.23 |
| Q4 2024 | 1,993,687 | 0 | — | $615.2M | 9.30% | $308.57 |
| Q3 2024 | 1,993,687 | +77,825 | +4.1% | $423.1M | 6.12% | $212.22 |
| Q2 2024 | 1,915,862 | +1,518,815 | +382.5% | $536.7M | 8.31% | $280.16 |
| Q1 2024 | 397,047 | 418,144 | -51.3% | $106.0M | 1.57% | $267.04 |
| Q4 2023 | 815,191 | +505,706 | +163.4% | $188.6M | 2.95% | $231.38 |
| Q3 2023 | 309,485 | +87,923 | +39.7% | $45.2M | 0.95% | $146.04 |
| Q2 2023 | 221,562 | — | — | $51.2M | 0.97% | $231.00 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did RTW INVESTMENTS, LP first disclose a MDGL position in 13F-HR filings?
RTW INVESTMENTS, LP first reported MADRIGAL PHARMACEUTICALS INC (MDGL) on its 13F-HR filing for the period ending 2023-06-30 (Q2 2023). The position has appeared on 12 reported quarters within Pactolio's tracked window.
What was RTW INVESTMENTS, LP's most recent quarter-over-quarter share-count change in MDGL?
RTW INVESTMENTS, LP held the same 1,993,687 shares of MDGL between Q4 2025 and Q1 2026 — the reported share count was unchanged quarter-over-quarter.
Does the implied price-per-share represent RTW INVESTMENTS, LP's cost basis in MDGL?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.