MERUS N V (SYN_N5749R100) — Institutional Holders & Hedge Fund Ownership
MERUS N V (SYN_N5749R100) institutional ownership: 14 hedge funds and institutional investors, holding 21.4M shares ($2.01B), as of Q3 2025, per SEC Form 13F-HR filings.
MERUS N V (SYN_N5749R100) institutional ownership tracks hedge funds, family offices, and asset managers that disclose 13F positions in SYN_N5749R100 each quarter. Pactolio aggregates these SEC Form 13F-HR filings into one view: top institutional holders, biggest QoQ buyers and sellers, and consolidated ownership changes for SYN_N5749R100.
The top SYN_N5749R100 shareholders by portfolio weight are Commodore Capital (16.20%), Paradigm Biocapital Advisors (12.18%), and Kryger (11.46%). In Q3 2025, Kryger made the largest position increase (+11.46%).
Top 10 Institutional Holders of MERUS N V (SYN_N5749R100) — Q3 2025
| # | Fund | Shares | Market Value | Portfolio Weight |
|---|---|---|---|---|
| 1 | Commodore Capital | 3,525,000 | $331.9M | 16.20% |
| 2 | Paradigm Biocapital Advisors | 4,373,770 | $411.8M | 12.18% |
| 3 | Kryger | 1,053,500 | $99.2M | 11.46% |
| 4 | Sand Grove Capital Management | 239,378 | $22.5M | 11.01% |
| 5 | Glazer Capital | 1,619,372 | $152.5M | 5.12% |
| 6 | Deerfield | 3,046,916 | $286.9M | 4.40% |
| 7 | Avoro Capital Advisors | 3,542,500 | $333.5M | 4.31% |
| 8 | Decagon Asset Management | 83,728 | $7.9M | 4.16% |
| 9 | Slotnik Capital | 90,000 | $8.5M | 3.05% |
| 10 | Caligan | 216,954 | $20.4M | 2.83% |
- 14Hedge funds holding
- 21,372,232Shares held (disclosed)
- $2.01B13F market value
- 4.24%Median portfolio weight
Ownership History
Quarter-by-quarter share count, market value, and portfolio conviction weight (up to 5 of the heaviest weight-by-portfolio funds) of SYN_N5749R100. Sourced from 13F filings; reflects long equity positions only.
Quarter-over-Quarter ActivityQ3 2025
The biggest weight-increase and weight-decrease changes among funds that hold SYN_N5749R100. Deltas compare the selected filing to the previous reporting quarter.
Top buyers
- Kryger+11.46% · +1,053,500 shares
- Sand Grove Capital Management+11.01% · +239,378 shares
- Glazer Capital+5.12% · +1,619,372 shares
Top sellers
- Caligan-3.87% · -440,045 shares
- Darwin Global Management-0.88% · -395,738 shares
- RTW Investments-0.65% · -1,975,276 shares
Options Activity
- Total calls300,000 (+300,000)
Ownership Statistics
- Funds holding
- 14
- Median weight
- 4.24%
- Largest holder
- Commodore Capital · 16.20%
- Smallest holder
- Polen Capital Management · 0.00%
- Shares held
- 21,372,232 (+1,116,594)
All Institutional HoldersSortable · searchable
All institutional investors (Max 50) holding SYN_N5749R100 in the selected quarter. Click a fund name to drill into its full 13F portfolio.
| 1 | Commodore Capital | 3,525,000 | $331.9M | 16.20% |
| 2 | Paradigm Biocapital Advisors | 4,373,770 | $411.8M | 12.18% |
| 3 | Kryger | 1,053,500 | $99.2M | 11.46% |
| 4 | Sand Grove Capital Management | 239,378 | $22.5M | 11.01% |
| 5 | Glazer Capital | 1,619,372 | $152.5M | 5.12% |
| 6 | Deerfield | 3,046,916 | $286.9M | 4.40% |
| 7 | Avoro Capital Advisors | 3,542,500 | $333.5M | 4.31% |
| 8 | Decagon Asset Management | 83,728 | $7.9M | 4.16% |
| 9 | Slotnik Capital | 90,000 | $8.5M | 3.05% |
| 10 | Caligan | 216,954 | $20.4M | 2.83% |
| 11 | RTW Investments | 2,025,277 | $190.7M | 2.35% |
| 12 | Pentwater Capital Management | 970,000 | $91.3M | 0.82% |
| 13 | Baker Bros. Advisors | 574,377 | $54.1M | 0.39% |
| 14 | Polen Capital Management | 11,460 | $1.1M | 0.00% |
Methodology & FAQ
Methodology: How We Track SYN_N5749R100 Institutional Holdings
Our data is systematically aggregated directly from quarterly Form 13F-HR disclosures submitted to the U.S. Securities and Exchange Commission (SEC).
- Who Must File (Reporting Threshold): This dataset includes filings from U.S. institutional investment managers, hedge funds, mutual funds, university endowments, and family offices managing at least $100 million in Section 13(f) securities (including equities, options, convertibles, ETFs, and warrants).
- What is Included (Data Scope): We capture long positions in Section 13(f) securities for MERUS N V (SYN_N5749R100). By SEC regulation, 13F filings do not require the disclosure of short positions, non-U.S. holdings, or OTC derivatives. Listed options are excluded from portfolio weight calculations to ensure comparability across filers.
- Portfolio Weight Explained (Metric Definition): “Portfolio Weight” shows how much of a fund's total reported 13F portfolio value (excluding listed options) is allocated to SYN_N5749R100 on the specific reporting date.
- How to Use This Data (Interpretation): Quarter-over-quarter changes in shares and portfolio weight reflect a combination of active trading and market price movements. These are descriptive metrics of fund allocation, not explicit buy or sell signals.
How do you measure hedge fund conviction and institutional concentration in SYN_N5749R100?
We evaluate fund conviction by looking at portfolio weight rather than just absolute share count. By tracking how the largest holders —such as Commodore Capital , Paradigm Biocapital Advisors , and Kryger as of Q3 2025— change their position sizing quarter-over-quarter, we help investors distinguish between deliberate position sizing changes and passive mark-to-market drift.
Does the SYN_N5749R100 ownership data include short interest or options?
SEC Form 13F mandates the disclosure of long positions in Section 13(f) securities, which includes equities and listed options (put and call contracts), but excludes short interest, swaps, and OTC derivatives by regulatory design. On this platform, listed options are excluded from portfolio weight calculations to ensure comparability across filers.
Are family offices and university endowments included in this SYN_N5749R100 data?
Yes. In addition to traditional hedge funds and large asset managers, any institutional entity exercising investment discretion over at least $100 million in Section 13(f) securities must file a Form 13F. This explicitly includes single-family offices and university endowments. If a qualifying family office or endowment holds SYN_N5749R100 stock, their allocation is systematically aggregated alongside traditional fund data.
When is the institutional ownership data updated, and is there a reporting lag?
Institutional investment managers are required to file their Form 13F within 45 days after the end of a calendar quarter (the standard “T+45” window). Our platform re-ingests new filings from the SEC EDGAR database on a nightly cycle, typically within 24–48 hours of publication, providing a point-in-time snapshot of reported consensus positioning for SYN_N5749R100 as of each filing date.