TANGO THERAPEUTICS (TNGX) — Institutional Holders & Hedge Fund Ownership
TANGO THERAPEUTICS (TNGX) institutional ownership: 5 hedge funds and institutional investors, holding 26.6M shares ($556.8M), as of Q1 2026, per SEC Form 13F-HR filings.
Track who bought and sold TANGO THERAPEUTICS (TNGX) this quarter — every hedge fund, family office, and institutional investor that filed an SEC Form 13F-HR for TNGX is aggregated here. The data covers every 13F filer that disclosed a TNGX position — top holders by portfolio weight, biggest quarterly buyers and sellers, and positioning shifts.
The top TNGX shareholders by portfolio weight are Caligan (3.56%), RTW Investments (2.77%), and Paradigm Biocapital Advisors (1.71%). In Q1 2026, RTW Investments made the largest position increase (+2.64%).
Top 5 Institutional Holders of TANGO THERAPEUTICS (TNGX) — Q1 2026
| # | Fund | Shares | Market Value | Portfolio Weight |
|---|---|---|---|---|
| 1 | Caligan | 2,408,798 | $50.4M | 3.56% |
| 2 | RTW Investments | 13,300,620 | $278.2M | 2.77% |
| 3 | Paradigm Biocapital Advisors | 4,009,679 | $83.9M | 1.71% |
| 4 | Deep Track | 2,750,000 | $57.5M | 1.19% |
| 5 | Deerfield | 4,146,813 | $86.8M | 1.02% |
- 5Hedge funds holding
- 26,615,910Shares held (disclosed)
- $556.8M13F market value
- 1.71%Median portfolio weight
Ownership History
Quarter-by-quarter share count, market value, and portfolio conviction weight (up to 5 of the heaviest weight-by-portfolio funds) of TNGX. Sourced from 13F filings; reflects long equity positions only.
Quarter-over-Quarter ActivityQ1 2026
The biggest weight-increase and weight-decrease changes among funds that hold TNGX. Deltas compare the selected filing to the previous reporting quarter.
Top buyers
- RTW Investments+2.64% · +11,809,392 shares
- Paradigm Biocapital Advisors+1.71% · +4,009,679 shares
- Deerfield+0.69% · +1,239,867 shares
Top sellers
- Caligan0.54% · -1,321,097 shares
Ownership Statistics
- Funds holding
- 5
- Median weight
- 1.71%
- Largest holder
- Caligan · 3.56%
- Smallest holder
- Deerfield · 1.02%
- Shares held
- 26,615,910 (+16,033,279)
All Institutional HoldersSortable · searchable
All institutional investors (Max 50) holding TNGX in the selected quarter. Click a fund name to drill into its full 13F portfolio.
| 1 | Caligan | 2,408,798 | $50.4M | 3.56% |
| 2 | RTW Investments | 13,300,620 | $278.2M | 2.77% |
| 3 | Paradigm Biocapital Advisors | 4,009,679 | $83.9M | 1.71% |
| 4 | Deep Track | 2,750,000 | $57.5M | 1.19% |
| 5 | Deerfield | 4,146,813 | $86.8M | 1.02% |
Methodology & FAQ
Methodology: How We Track TNGX Institutional Holdings
Our data is systematically aggregated directly from quarterly Form 13F-HR disclosures submitted to the U.S. Securities and Exchange Commission (SEC).
- Who Must File (Reporting Threshold): This dataset includes filings from U.S. institutional investment managers, hedge funds, mutual funds, university endowments, and family offices managing at least $100 million in Section 13(f) securities (including equities, options, convertibles, ETFs, and warrants).
- What is Included (Data Scope): We capture long positions in Section 13(f) securities for TANGO THERAPEUTICS INC (TNGX). By SEC regulation, 13F filings do not require the disclosure of short positions, non-U.S. holdings, or OTC derivatives. Listed options are excluded from portfolio weight calculations to ensure comparability across filers.
- Portfolio Weight Explained (Metric Definition): “Portfolio Weight” shows how much of a fund's total reported 13F portfolio value (excluding listed options) is allocated to TNGX on the specific reporting date.
- How to Use This Data (Interpretation): Quarter-over-quarter changes in shares and portfolio weight reflect a combination of active trading and market price movements. These are descriptive metrics of fund allocation, not explicit buy or sell signals.
How do you measure hedge fund conviction and institutional concentration in TNGX?
We evaluate fund conviction by looking at portfolio weight rather than just absolute share count. By tracking how the largest holders —such as Caligan , RTW Investments , and Paradigm Biocapital Advisors as of Q1 2026— change their position sizing quarter-over-quarter, we help investors distinguish between deliberate position sizing changes and passive mark-to-market drift.
Does the TNGX ownership data include short interest or options?
SEC Form 13F mandates the disclosure of long positions in Section 13(f) securities, which includes equities and listed options (put and call contracts), but excludes short interest, swaps, and OTC derivatives by regulatory design. On this platform, listed options are excluded from portfolio weight calculations to ensure comparability across filers.
Are family offices and university endowments included in this TNGX data?
Yes. In addition to traditional hedge funds and large asset managers, any institutional entity exercising investment discretion over at least $100 million in Section 13(f) securities must file a Form 13F. This explicitly includes single-family offices and university endowments. If a qualifying family office or endowment holds TNGX stock, their allocation is systematically aggregated alongside traditional fund data.
When is the institutional ownership data updated, and is there a reporting lag?
Institutional investment managers are required to file their Form 13F within 45 days after the end of a calendar quarter (the standard “T+45” window). Our platform re-ingests new filings from the SEC EDGAR database on a nightly cycle, typically within 24–48 hours of publication, providing a point-in-time snapshot of reported consensus positioning for TNGX as of each filing date.