Darwin Global Management, Ltd.: INSMED INC (INSM): Quarterly 13F Position History
As of Q1 2026, Darwin Global Management, Ltd. reported 16,805,184 shares of INSMED INC (INSM), worth $2.6B and representing 68.3% of its 13F equity book. Quarter-over-quarter share count change: 4,128,093 (-19.7%) . The position first appeared in Q2 2024 and has been disclosed across 8 13F-HR filings in Pactolio's tracked window.
- 16,805,184Shares Held (Latest Filing)
- $2.6BReported Market Value (Latest Filing)
- 68.3%Portfolio Weight (% of 13F Equity Book)
- 4,128,093Quarter-over-Quarter Share Change
- -$1.1BQuarter-over-Quarter Value Change
- 20,933,277Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 8 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 16,805,184 | 4,128,093 | -19.7% | $2.6B | 68.3% | $153.3 |
| Q4 2025 | 20,933,277 | +475,832 | +2.3% | $3.6B | 73.8% | $174.1 |
| Q3 2025 | 20,457,445 | +1,112,824 | +5.8% | $2.9B | 80.5% | $141.7 |
| Q2 2025 | 19,344,621 | +3,946,646 | +25.6% | $1.9B | 80.8% | $99.5 |
| Q1 2025 | 15,397,975 | +2,437,437 | +18.8% | $1.2B | 82.1% | $78.0 |
| Q4 2024 | 12,960,538 | +2,463,261 | +23.5% | $894.8M | 84.8% | $69.0 |
| Q3 2024 | 10,497,277 | +6,956,182 | +196.4% | $766.3M | 62.3% | $73.0 |
| Q2 2024 | 3,541,095 | — | — | $237.1M | 27.6% | $67.0 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did Darwin Global Management, Ltd. first disclose a INSM position in 13F-HR filings?
Darwin Global Management, Ltd. first reported INSMED INC (INSM) on its 13F-HR filing for the period ending 2024-06-30 (Q2 2024). The position has appeared on 8 reported quarters within Pactolio's tracked window.
What was Darwin Global Management, Ltd.'s most recent quarter-over-quarter share-count change in INSM?
Between Q4 2025 and Q1 2026, Darwin Global Management, Ltd. reduced its INSM position by 4,128,093 shares (-19.7%), leaving 16,805,184 shares at a market value of $2.6B.
Does the implied price-per-share represent Darwin Global Management, Ltd.'s cost basis in INSM?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.