Samsara BioCapital, LLC: SEPTERNA INC (SEPN): Quarterly 13F Position History
As of Q1 2026, Samsara BioCapital, LLC reported 3,149,128 shares of SEPTERNA INC (SEPN), worth $75.7M and representing 7.4% of its 13F equity book. The position first appeared in Q4 2024 and has been disclosed across 6 13F-HR filings in Pactolio's tracked window.
- 3,149,128Shares Held (Latest Filing)
- $75.7MReported Market Value (Latest Filing)
- 7.4%Portfolio Weight (% of 13F Equity Book)
- 0Quarter-over-Quarter Share Change
- -$12.1MQuarter-over-Quarter Value Change
- 3,149,128Peak Reported Shares (Historical)
Quarterly 13F-HR Disclosure History Source: SEC 13F-HR filings, 6 quarter s
| Quarter | Shares | QoQ Share Change | Share Change (%) | Market Value | Weight | Implied Price |
|---|---|---|---|---|---|---|
| Q1 2026 | 3,149,128 | 0 | — | $75.7M | 7.4% | $24.0 |
| Q4 2025 | 3,149,128 | 0 | — | $87.8M | 9.1% | $27.9 |
| Q3 2025 | 3,149,128 | 0 | — | $59.2M | 7.7% | $18.8 |
| Q2 2025 | 3,149,128 | 0 | — | $33.3M | 6.8% | $10.6 |
| Q1 2025 | 3,149,128 | +380,608 | +13.7% | $18.2M | 3.3% | $5.8 |
| Q4 2024 | 2,768,520 | — | — | $63.4M | 8.7% | $22.9 |
Methodology & FAQ
How This Position History Is Sourced
Each row is one SEC Form 13F-HR filing disclosing this position. Share count, market value, and reported quarter are taken verbatim from the filing; portfolio weight is recomputed against the same filing's total reported equity book. Implied price-per-share is market value divided by shares — a quarter-end mark, not the manager's cost basis. See the full methodology document for the normalization rules.
When did Samsara BioCapital, LLC first disclose a SEPN position in 13F-HR filings?
Samsara BioCapital, LLC first reported SEPTERNA INC (SEPN) on its 13F-HR filing for the period ending 2024-12-31 (Q4 2024). The position has appeared on 6 reported quarters within Pactolio's tracked window.
What was Samsara BioCapital, LLC's most recent quarter-over-quarter share-count change in SEPN?
Samsara BioCapital, LLC held the same 3,149,128 shares of SEPN between Q4 2025 and Q1 2026 — the reported share count was unchanged quarter-over-quarter.
Does the implied price-per-share represent Samsara BioCapital, LLC's cost basis in SEPN?
No. The implied price-per-share column is the 13F-HR reported market value divided by reported share count on the filing date (end of quarter). It is a quarter-end mark, not a cost basis or transaction price. Use it as a sanity check on the value column, not as an indicator of the manager's entry or exit price.